Should GLP-1 Be in Your Preop Toolkit—or Not?

July 18, 2025 1 min read Premium comments

Diagram illustrating how GLP-1 receptor agonists regulate appetite, slow gastric emptying, and affect insulin and glucagon secretion via actions on the small intestine, brain, stomach, and pancreas. / Courtesy of Wikimedia Commons with Myluckynumber7

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The age of Ozempic isn’t just about shrinking waistlines and skyrocketing stock prices. It’s now knocking on the doors of the OR. A new review article in the July 10, 2025, issue of The Journal of Bone and Joint Surgery dares to ask: Is there a role for GLP-1 receptor agonists (RAs) in orthopedic surgery?

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