GLP-1 RAs Reduce Complications in Morbidly Obese Patients?

Attempting to change patient obesity levels prior to total knee arthroplasty is difficult, under the best conditions. A team from New York’s Hospital for Special Surgery (HSS) set out to evaluate the effect of perioperative use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in this population. Their work, “Glucagon-Like Peptide-1 Receptor Agonists Decrease Medical and Surgical Complications in Morbidly Obese Patients Undergoing Primary TKA,” appears in the February 19, 2025 edition of The Journal of Bone and Joint Surgery.     (