The MACI Biopsy Question: Why Only One in Three Patients Returns for Implantation

September 10, 2026 1 min read Premium comments

Courtesy of Morouço, P.; Fernandes, C.; Lattanzi, W. / Wikimedia Commons, CC BY 4.0

matrix-induced autologous chondrocyte implantationcartilage biopsyknee chondral defectstaged procedureimplantation rate

Matrix-induced autologous chondrocyte implantation is commonly described as a two-stage procedure. First, the surgeon arthroscopically evaluates the knee, treats associated pathology, and harvests a cartilage biopsy. The patient then returns for implantation of the expanded autologous chondrocytes.

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