DiscGenics, Inc., a clinical-stage biopharmaceutical company based in Salt Lake City, Utah, has announced the appointment of Jeff Poole to the role of Chief Financial Officer. The company’s product candidate, IDCT, is an allogenic injectable discogenic cellular therapy for lumbar degenerative disc disease (DDD). IDCT is currently being tested in a Phase 1/2 clinical trial at multiple sites in the U.S. and another trial in Japan. The U.S. trial completed enrollment earlier in 2020 and, until now, the company has operated without a Chief Financial Officer.
Jeff Poole Appointed First Chief Financial Officer of DiscGenics

Jeff Poole is the former VP of Finance for the Spine and Biologics division of Medtronic, plc. He oversaw the global business unit’s $2.5 billion annual revenue and has developed international experience over his 13 years of financial leadership positions at Medtronic. He has also lived in Japan for over 4 years and is fluent in the language, another asset to the company with strong ties to investment and clinical experience in Japan.
In a company press release Poole said, “I am thrilled to be joining DiscGenics because I truly believe its innovative regenerative therapy addresses an unmet clinical need and could significantly alter the definition of Standard of Care for patients suffering from spinal disc degeneration.”
Chief Executive Officer and Chairman of the Board of Directors, Flagg Flannigan, is pleased to have Poole help the company as “we move through our final clinical stages and evaluate various financing and commercial opportunities going forward in the U.S. and Japan.”
DiscGenics recently received $50 million in Series C funding, bringing total fundraising to over $71 million. The funds are being used to continue the trials currently underway, as well as to conduct preclinical work on use of the product in cervical DDD, post-fusion adjacent levels, and post-discectomy use.

Discussion
This is a fascinating development. In my practice we've seen similar outcomes with the revised protocol. The key differentiator seems to be patient selection criteria. Has anyone else noticed the correlation with BMI thresholds?
Great point. I'd push back slightly on the conclusion, the sample size in the cited study is too small to draw population-level inferences. That said, the directional signal is compelling and worth a larger RCT.
We implemented a similar approach last year. Early results are promising but we're still gathering 12-month follow-up data. Happy to share our protocol if anyone is interested.
Join the conversation
Orthopedic professionals are discussing this. Sign in and upgrade to read every comment and add your voice.