Minimus Spine Inc., headquartered in Austin, Texas, has signed its first European distribution agreement and completed its first commercial order.
Minimus Spine Signs Initial EU Distribution Deal

The agreement was signed with MOSS S.p.A., an Italian company that has been granted exclusive distribution rights for Italy, Germany, Switzerland and the UK.
According to Minimus Spine’s CEO and President David M. Hooper, Ph.D., “We are happy to be working with Franco Papa and his company MOSS. MOSS has a range of novel products tailored for the interventional radiology community and this provides us with key distribution channels in Europe. Our plan is to introduce Triojection to select accounts over the next few months and expand the launch with additional distributors next year.”
Franco Papa, president and CEO of MOSS, added, “We are pleased to be partnering with Minimus in their European commercialization effort. Over the past months, we introduced the Triojection concept to leading physicians at selected European reference centres with the aim of significantly promoting a successful market penetration.”
Dr. Hooper commented to OTW, “The agreement gives Minimus distribution channels in several European countries and enables us to introduce Triojection to a wider group of physicians. To date, we have self-limited the availability of Triojection to our post-market study comparing to discectomy. While we are continuing to enroll that study, we are nearing the completion of enrollment. Now, we are aiming to leverage both our CE Mark and the coming clinical data to build a business around Triojection and the use of ozone in the treatment of herniated discs. Once we start to demonstrate commercial traction in Europe, we should be in position to accelerate our efforts pertaining to the U.S. regulatory pathway.”

Discussion
This is a fascinating development. In my practice we've seen similar outcomes with the revised protocol. The key differentiator seems to be patient selection criteria. Has anyone else noticed the correlation with BMI thresholds?
Great point. I'd push back slightly on the conclusion, the sample size in the cited study is too small to draw population-level inferences. That said, the directional signal is compelling and worth a larger RCT.
We implemented a similar approach last year. Early results are promising but we're still gathering 12-month follow-up data. Happy to share our protocol if anyone is interested.
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