In Indiana, a new effort is underway to advance understanding between university-based researchers and “the market.”
Indiana University/IURTC, AcceLINX Form Partnership

Indiana University (IU) and its affiliate, the Indiana University Research and Technology Corporation (IURTC), are partnering with AcceLINX, the business accelerator developed and launched by OrthoWorx.
The goal? Develop new or more cost-effective therapies for musculoskeletal diseases.
Tony Armstrong, president and CEO of IURTC and associate vice president in the IU Office of the Vice President for Engagement, said in the December 5, 2017 news release, “If these inventors lack the commercial and operating experience to advance a technology, AcceLINX has the expertise and the network of resources to partner with us to help provide a quicker transition from idea to successful product or service.”
AcceLINX president and CEO Sheryl Conley said, “Indiana University has an outstanding record of developing technologies in the health sector. We look forward to assisting its researchers and IURTC in bringing new musculoskeletal innovations to market.”
Sheryl Conley told OTW, “This partnership is intended to address the challenges that many university based-researchers face, the most pressing of which would be a greater understanding of what the market is looking for in terms of product benefits and proof of performance.”
“The program involves a number of visits to the IU campus by AcceLINX consultants each year to meet with researchers to understand their inventions and provide guidance in key areas. There is also the opportunity to engage in more detailed consulting projects to address key unknowns.”

Discussion
This is a fascinating development. In my practice we've seen similar outcomes with the revised protocol. The key differentiator seems to be patient selection criteria. Has anyone else noticed the correlation with BMI thresholds?
Great point. I'd push back slightly on the conclusion, the sample size in the cited study is too small to draw population-level inferences. That said, the directional signal is compelling and worth a larger RCT.
We implemented a similar approach last year. Early results are promising but we're still gathering 12-month follow-up data. Happy to share our protocol if anyone is interested.
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