It’s been four years since our friend Jeffrey Guyer passed away.
Guyer Family Keeps Jeffrey’s Hope Alive

His mother and father, Shelly and Rick Guyer, M.D., and their family have kept hope alive that a cure can be found for the cancer that took the young engineer’s life.
We are honored to provide our readers with a chance to participate in this effort. Below is a letter from the family to tell you how you can help. –OTW Staff
Dear Family and Friends,
June 6, 2011 will forever be etched in our memories. It was when Jeffrey Guyer passed away. He was our beloved son, brother, husband and friend.
He was an amazing 30 year old young man, full of life, already so accomplished and with so much still to give. He was taken away much too soon by a very rare form of sarcoma which accounts for 1% of all cancers.
When Jeffrey was first diagnosed, and throughout his long year of chemotherapy, surgeries, clinical trials and pain, he worked relentlessly to start fundraising to help raise money for sarcoma research. That first year he raised over $100, 000. Before he passed away, he asked that we continue his fundraising so maybe just one person’s life can be saved. We have raised over $350, 000; however this is not nearly enough funding to carry out the necessary research studies that will help to one day find a cure to this devastating cancer.
We are asking for your help. We realize that everyone has their favorite charity, their own family member who has died from something terrible, and their own passionate cause. We are not asking you to run or walk in a 5K race or bake cookies or cakes for a bake sale or buy a fancy new outfit for a charity event. We are asking that you give however big or small in memory of Jeffrey.
We have started a fund at MD Anderson Cancer Center in Houston which is an amazing institution dedicated to the treatment and research of all kinds of cancer.
A simple click to the following link will ensure that all donations will go directly to the Jeffrey Allen Guyer Sarcoma Research Fund.
To ensure the donation goes to our designated account, please follow these simple steps.
- Click website above
- Click Honor a Loved One
- Click Give Now
- Under billing information, click box “Yes! I’d like to choose where my donation will go”
- Click “Other”
- Type in “Guyer” in the drop box.
If you prefer to donate by check, click on the same website as above and you download a form from the box “donate by mail”. Just be sure to put “Guyer” in the subject line on your check.
Please honor the memory of our Jeffrey and help support our passionate cause. As always, we appreciate all that you have done and thank you in advance of all that you will do. It touches our hearts.
Shelly, Rick, Kim, Dan, Lindsay and Autumn

Discussion
This is a fascinating development. In my practice we've seen similar outcomes with the revised protocol. The key differentiator seems to be patient selection criteria. Has anyone else noticed the correlation with BMI thresholds?
Great point. I'd push back slightly on the conclusion, the sample size in the cited study is too small to draw population-level inferences. That said, the directional signal is compelling and worth a larger RCT.
We implemented a similar approach last year. Early results are promising but we're still gathering 12-month follow-up data. Happy to share our protocol if anyone is interested.
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