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Home/Large Joints and Extremities/Magnets Used To Concentrate Stem Cells
Large Joints and Extremities

Magnets Used To Concentrate Stem Cells

February 24, 2015 1 min read Premium comments

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Magnets Used To Concentrate Stem Cells
Source: Wikimedia Commons and marshallsumter
Secondary

A team at Hiroshima University Hospital, Hiroshima, Japan, in a world first procedure, used magnets to concentrate iron-laced stem cells around damaged cartilage. The surgeon, Mitsuo Ochi, M.D., said that the endoscopic surgery was easier on the patient than other approaches.

Prior to the surgery, the team extracted mesenchymal stem cells from the bone marrow of an 18-year-old female high school student and cultivated them with iron powder to create magnetic stem cells.

The team injected the iron-laced stem cells into the patient’s right knee joint and used the magnet to concentrate the cells in areas where the patient’s knee cartilage had been lost. The team expects that the stem cells will develop into cartilage.

According to the team, previous tests of this procedure on animals have been successful. . They anticipate that it will take a year to determine the effectiveness of this novel regenerative technique.

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Discussion

14
DS
Dr. Sarah MitchellOrthopedic Surgeon · Mayo Clinic

This is a fascinating development. In my practice we've seen similar outcomes with the revised protocol. The key differentiator seems to be patient selection criteria. Has anyone else noticed the correlation with BMI thresholds?

8
JT
James Thornton, MDSpine Fellow · HSS

Great point. I'd push back slightly on the conclusion, the sample size in the cited study is too small to draw population-level inferences. That said, the directional signal is compelling and worth a larger RCT.

5
RP
R. PatelSports Medicine · Stanford

We implemented a similar approach last year. Early results are promising but we're still gathering 12-month follow-up data. Happy to share our protocol if anyone is interested.

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