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Home/Biologics/Coral Grown to Repair Bone
Biologics

Coral Grown to Repair Bone

October 27, 2014 1 min read Premium comments

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Coral Grown to Repair Bone
Source: Wikimedia Commons and Rob Lavinsky
Secondary

On a site far from any ocean a man is growing coral in a tank with the expectation it will help heal damaged bone. Unlike animal and human bones, coral is not rejected by the body, according to medical experts at the coral-growing company in Israel’s Negev desert called CoreBone.

The visionary founder is Assaf Shaham who founded his laboratory six years ago at a cost of $2.5 million. He told Ian Lee of CNN that, “In six years of growing corals, I haven’t left these four walls for more than 12 hours—not even once. For me, it’s 100% learning as I go. I take the mother colony, and I cut off a branch of the coral with a diamond saw. Then I glue it to another base made out of cement.”

Lee reports that Shaham’s ecosystem needs constant care to ensure that the water’s salinity, temperature, and chemical make-up are perfect. If there are any variations the coral could die, he said. Workers explain that the fish swimming around each tank are the “worker bees” of the artificial reef. They eat the algae growing on the coral, their feces helps feed the coral, and their movements in the water keep the coral strong.

Shaham’s, ambitious experiment appears to be thriving for, according to the press release, the coral in the lab is growing at ten times the normal rate. Shaham expects to receive a decision about the medical use of his coral from regulatory authorities in Europe and the United States sometime next year. He sells a small container of his coral for $250.

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Discussion

14
DS
Dr. Sarah MitchellOrthopedic Surgeon · Mayo Clinic

This is a fascinating development. In my practice we've seen similar outcomes with the revised protocol. The key differentiator seems to be patient selection criteria. Has anyone else noticed the correlation with BMI thresholds?

8
JT
James Thornton, MDSpine Fellow · HSS

Great point. I'd push back slightly on the conclusion, the sample size in the cited study is too small to draw population-level inferences. That said, the directional signal is compelling and worth a larger RCT.

5
RP
R. PatelSports Medicine · Stanford

We implemented a similar approach last year. Early results are promising but we're still gathering 12-month follow-up data. Happy to share our protocol if anyone is interested.

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