LinkedInXFacebook
Subscribe
Orthopedics This Week
  • My Feed
  • |Posts
  • |Events
  • |MSK Innovations
  • |Power Rankings
  • |Masterclasses
  • |Technology Awards
  • Press Releases
  • |Advertising
  • |Job Board
  • Spine
  • ◆Joints
  • ◆Upper Extremities
  • ◆Foot & Ankle
  • ◆Sports Medicine
  • ◆Pain Mgmt
  • ◆Trauma
  • ◆Biologics
  • ◆Technology
  • ◆People
  • ◆Company News
  • ◆Legal & Regulatory
Home/Large Joints and Extremities/Good News For Dark Chocolate
Large Joints and Extremities

Good News For Dark Chocolate

July 28, 2014 2 min read Premium comments

Advertisement

Good News For Dark Chocolate
Source: Wikimedia Commons and Alpunin
Secondary

Dark chocolate lovers rejoice. Researchers have found that eating dark chocolate may help people with peripheral artery disease (PAD) walk a little better. While the study was small with only 20 participants—14 men and six women—the results were clear. The eaters of the dark chocolate showed an 11% increase in their maximum walking distance compared to no change in those patients who ate the same amount of milk chocolate. The study was limited to patients with intermittent claudication (IC). IC involves impaired blood flow to the limbs, especially during exercise.

Salynn Boyles, a contributing writer for MedPage Today reported the study.

The lead researcher was Lorenzo Loffredo, M.D., of Sapienza University, Rome, Italy.   He reported on the study in the Journal of the American Heart Association. The goal of Loffredo’s work was to determine whether eating dark chocolate could improve walking autonomy in PAD patients with IC.

Researchers drew fasting blood samples from the participants at 8 am in the morning and also performed ankle brachial index (ABI) and flow mediated dilation (FMD) exams.   At 9 am the subjects performed a treadmill test and 2 minutes after completing the treadmill test the investigators measured the subject’s maximal walking distance (MWD) and maximal walking time (MWT). They also measured their ABI again.

At 9:25 am they gave the participants the chocolate (40 grams). The dark chocolate was 85% cocoa and the milk chocolate was 35% cocoa. They had 15 minutes to eat it. At 11:25 am the researchers drew blood samples again. At 11:30 am they performed a second ABI at rest and FMD, and at 11:50 am the participants underwent a second treadmill test. Once again, doctors performed an ABI two minutes after they measured MWD and MWT.

“This study has implications and limitations, ” the researchers wrote. “It should be considered a proof-of-concept study that is potentially useful to understand the mechanism of disease related to IC but not transferable to clinical practice because of small sample size and the disease of the study.”

Natalie Evans, M.D., of the Cleveland Clinic, who was not involved with the study, said “There is a huge population out there with peripheral artery disease, but only about 11% of them actually have intermittent claudication, ” she said. “I think it would be really interesting to find out what impact dark chocolate would have on [patients without this complication].”

React:

Discussion

14
DS
Dr. Sarah MitchellOrthopedic Surgeon · Mayo Clinic

This is a fascinating development. In my practice we've seen similar outcomes with the revised protocol. The key differentiator seems to be patient selection criteria. Has anyone else noticed the correlation with BMI thresholds?

8
JT
James Thornton, MDSpine Fellow · HSS

Great point. I'd push back slightly on the conclusion, the sample size in the cited study is too small to draw population-level inferences. That said, the directional signal is compelling and worth a larger RCT.

5
RP
R. PatelSports Medicine · Stanford

We implemented a similar approach last year. Early results are promising but we're still gathering 12-month follow-up data. Happy to share our protocol if anyone is interested.

Join the conversation

Orthopedic professionals are discussing this. Sign in and upgrade to read every comment and add your voice.

Subscribe

Get Full Access

Read every OTW article and join member discussions for $24.99/month.

Get Full Access

Advertisement

Advertisement

Advertisement

Orthopedics This Week

The most trusted source in orthopedic industry news since 2005. Covering spine, joints, trauma, biologics, and the business of orthopedics.

A publication of RRY Publications, LLC

LinkedInXFacebook

Categories

  • Spine
  • Joints
  • Upper Extremities
  • Foot & Ankle
  • Sports Medicine
  • Pain Mgmt
  • Trauma
  • Biologics
  • Technology
  • People
  • Company News
  • Legal & Regulatory

Resources

  • Subscribe
  • Community Posts
  • Job Board
  • Press Release Opportunities
  • Power Rankings
  • About OTW
  • Advertise
  • Contact Us

Get Full Access

Unlimited articles, community posts, and Power Rankings.

Get Full Access

Plans start at $24.99/mo · Annual saves 20%

© 2026 Orthopedics This Week · RRY Publications, LLC

Privacy PolicyTerms of ServiceCookie Policy