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Home/Vitamin D and Calcium Pills: Not Enough Proof?

Vitamin D and Calcium Pills: Not Enough Proof?

February 27, 2013 1 min read Premium comments

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Vitamin D and Calcium Pills: Not Enough Proof?
Source: Wikimedia Commons and ChildofMidnight
Secondary

The American Society for Bone and Mineral Research (ASBMR) is wondering about the new recommendations by the U.S. Preventive Services Task Force (USPSTF) that address the use of the combination of vitamin D and calcium supplements to prevent bone fractures. The USPSTF statement suggests that there is not enough evidence, one way or the other, about how supplements affect bone fractures for men and premenopausal women.

The ASBMR indicates that the USPSTF’s recommendations differ from the 2010 Institute of Medicine’s (IOM) findings, primarily because these recommendations are based only on fracture outcomes, while the IOM included an examination of the underlying biology of the impact of calcium and vitamin D.

“The ASBMR continues to support the recommendations of the IOM because they are based on a broader evaluation of the data rather than only fracture outcomes, ” says Sundeep Khosla, M.D., in the February 25, 2013 news release. Dr. Khosla is past president of the ASBMR and a practicing endocrinologist and research scientist at the Mayo Clinic at Rochester, Minnesota.

The ASBMR has long supported that calcium and vitamin D are important to bone health and the best way to get them is through food that is naturally rich in these supplements. Calcium and vitamin D are the most crucial, yet simple, first steps in promoting good bone health.

“Research has shown us that healthy adults who are receiving the recommended amount of calcium and vitamin D in their diet and through sunlight exposure, need not take supplements for bone health, ” says Cliff Rosen, M.D., Past President of ASBMR and Director of Clinical and Translational Research and a Senior Scientist at Maine Medical Center’s Research Institute in Scarborough, Maine. “But the report leaves out a crucial and large population—the elderly, especially those at high risk for fractures in assisted living and nursing home facilities. This population has less exposure to sunlight and is at high risk for hip fracture. They should be receiving supplements. The evidence generally supports benefits of calcium and vitamin D for building strong skeletons and preventing fractures and bone loss in high risk, elderly individuals.”

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Discussion

14
DS
Dr. Sarah MitchellOrthopedic Surgeon · Mayo Clinic

This is a fascinating development. In my practice we've seen similar outcomes with the revised protocol. The key differentiator seems to be patient selection criteria. Has anyone else noticed the correlation with BMI thresholds?

8
JT
James Thornton, MDSpine Fellow · HSS

Great point. I'd push back slightly on the conclusion, the sample size in the cited study is too small to draw population-level inferences. That said, the directional signal is compelling and worth a larger RCT.

5
RP
R. PatelSports Medicine · Stanford

We implemented a similar approach last year. Early results are promising but we're still gathering 12-month follow-up data. Happy to share our protocol if anyone is interested.

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