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Home/Large Joints and Extremities/PRP Treatment for Cartilage Tears
Large Joints and Extremities

PRP Treatment for Cartilage Tears

August 10, 2012 1 min read Premium comments

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PRP Treatment for Cartilage Tears
Bone marrow. Source: Wikimedia Commons and Bobgligiano
Secondary

Additional therapeutic uses for platelet rich plasma (PRP) have come from research conducted in Bologna, Italy. PRP can be a safe and effective treatment for cartilage tears in athletes according to a study led by Elizaveta Kon, M.D. director of the Nano-Biotechnology Laboratory at the Rizzoli Orthopaedic Institute, Bologna.

“Using PRP therapy to repair cartilage is still relatively experimental, but studies like this show it’s not only safe but also offers a significant improvement in function and quality of life for patients, ” said Kon in the July 14 news release. “None of the patients treated experienced complications like infection, deep vein thrombosis or fever, ” she said.

For the study, researchers treated 180 patients for chronic pain or swelling of the knee with either PRP therapy or viscosupplementation, which is a more common hyaluronic acid-based treatment for cartilage damage. A total of 109 patients, who had an average age of 56, stayed with the study for a final evaluation. Both treatment groups demonstrated significant improvement based on higher post-treatment IKDC scores, which measure pain and basic function in follow-up interviews.

 “As athletic participation has grown, ” Kon noted, “new problems like cartilage lesions or tears continue to emerge. Finding the right approach to treatment is difficult, but PRP has emerged as a viable option according to our research.” Kon added that long-term follow-ups for PRP treatments are needed to further evaluate the overall effectiveness of the therapy for future patients.

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Discussion

14
DS
Dr. Sarah MitchellOrthopedic Surgeon · Mayo Clinic

This is a fascinating development. In my practice we've seen similar outcomes with the revised protocol. The key differentiator seems to be patient selection criteria. Has anyone else noticed the correlation with BMI thresholds?

8
JT
James Thornton, MDSpine Fellow · HSS

Great point. I'd push back slightly on the conclusion, the sample size in the cited study is too small to draw population-level inferences. That said, the directional signal is compelling and worth a larger RCT.

5
RP
R. PatelSports Medicine · Stanford

We implemented a similar approach last year. Early results are promising but we're still gathering 12-month follow-up data. Happy to share our protocol if anyone is interested.

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